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| ��μ뿬�윭 諛⑸쾿�뱾�씠 �엳寃좎��留�, 理쒓렐 媛��옣 留롮씠 �벐�씠�뒗 寃껋씠 MALDI-TOF-MS�씪�뒗 諛⑸쾿�씠�떎. �씠踰� �떎�뿕�뿉�꽌�뒗�씠�윭�븳 MALDI-TOF-MS諛⑸쾿�쓣 �궗�슜�빐 二쇱뼱吏� �떒諛깆쭏�씠 �뼱�뼡 �떒諛깆쭏�씤吏� 援щ퀎�빐蹂몃떎. 2. Data & Result 誘몄���쓽 �떒諛깆쭏 A瑜� �듃由쎌떊�쑝濡� 媛��닔遺꾪빐 �떆�궓 �뮘, MALDI-TOF 吏덈웾遺꾩꽍湲곕줈 �렔����씠�뱶 議곌컖�뱾�쓽 吏덈웾�쓣 痢≪젙�븯����떎. �븘�옒�뒗 peak媛� 鍮꾧탳�쟻 �넂��� �렔����씠�뱶�뱾�쓽 寃곌낵�씠�떎. m/z SN Quality Fac Res. Intens. Area 690.032 7.4 77 567 70.71 144 1481.096 20.6 1027 1499 284.13 649 1569.300 76. |
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| 諛쒗슚�쑀 �뿉 ����븳 �궡�슜 �엯�땲�떎. 諛쒗슚�쑀 / �뀪. �꽌濡� �뀫. 蹂몃줎 1. 諛쒗슚�쑀�쓽 �쁺�뼇�쟻 媛�移� 1.1.B vitamins 1.2.Lactose 1.3.Protein 1.4.Lipids 1.5.Minerals 2. �옣湲곕뒫�뿉 愿��젴�맂 諛쒗슚�쑀�쓽 湲곕뒫 2.1.Gut microflora 2.2.Gut-associated immune response 2.3.Laxation 3. 諛쒗슚�쑀��� �옣 吏덊솚 3.1.Lactase deficiency and lactose maldigestion 3.2.Diarrheal diseases 3.3.Colon cancer 3.4.Allergic reactions 3.5.Safety �뀬. 寃곕줎 �뀭. Reference ��� |
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| ��λ뒗 2-D gel electrophoresis 湲곗닠怨� MALDI MS 遺꾩꽍 湲곗닠�쓽 諛쒕떖�쓣 怨꾧린濡� ����웾 �슚�뒫 寃��깋(High Through put Screening : HTS) 湲곕뒫�쓣 �솗蹂댄븿�쑝濡쒖뜥 �뿰援� 媛��냽�븯�쓽 �넗���瑜� 留덈젴�븯����떎怨� �븷 �닔 �엳�뒿�땲�떎. 洹몃윭�굹 �봽濡쒗뀒�삤誘뱀뒪�뒗 �씠�윭�븳 �떎�뼇�븳 �쟻�슜�뿉�룄 遺덇뎄�븯怨� �빐寃고빐�빞 �븷 湲곗닠�쟻�씤 �븳怨꾨�� 媛�吏�怨� �엳�뼱 �씠�뱾�쓣 洹밸났�븯湲� �쐞�븳 �뿰援ш�� �븘�슂�븯�떎. 4) Proteome Analysis�쓽 �쟾諛섏쟻�씤 Work Flow �몺 Sample preparation �몼 2-D Electrophoresis �몾 Staining �몿 Image Acquisition �뫀 Image Analysis |
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| ��� screening)�씠 媛��뒫�븳 2-D �쟾湲곗쁺�룞 遺꾩꽍怨� MALDI-TOF (matrix-assisted laser desorption ionization time of flight) �뿉 �쓽�븳 �옄�룞�솕�맂 �떒諛깆쭏 遺꾩옄 援ъ“ 遺꾩꽍 湲곗닠 諛� �씠 �뱾�쓣 吏��썝�븯�뒗 �깮臾쇱젙蹂댄븰 (Bioinformatics)�쓽 諛쒖쟾怨� �뿰怨꾨릺�뼱 �엳�떎. �뵲�씪�꽌, �봽濡쒗뀒�삤誘뱀뒪�뒗 �꽭�룷�쓽 �깮由ъ쟻 �긽�깭蹂��솕�뿉 �뵲瑜� 遺꾩옄�쟻�씤 �쁽�긽怨� �꽭遺��쟻�씤 湲곗쟾�쓣 諛쒓뎬�븷 肉먮쭔 �븘�땲�씪 �뼱�뼸寃� �떒諛깆쭏�쓽 �몴�쁽�삎 (phenotype)�씠 吏덈퀝怨� �빟臾� 泥섎━�뿉 �뵲�씪 蹂��솕�븯�뒗 吏�瑜� 遺꾩꽍 �븷 �닔 �엳怨�, �씠濡� �씤�빐 �빟臾쇳몴�쟻�쓽 �떇蹂꾧낵 寃�利앹쓣 �븷 �닔 �엳寃� �맂�떎. �떎�젣濡�, �봽濡쒗뀒�삤誘뱀뒪媛� �빟臾쇳몴�쟻諛쒓뎬�뿉�꽌�룄 媛��옣 媛뺣젰�븳 湲� |
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| �빆怨듭옄�쑀�솕,留덉���똿,釉뚮옖�뱶,釉뚮옖�뱶留덉���똿,湲곗뾽,�꽌鍮꾩뒪留덉���똿,湲�濡쒕쾶,寃쎌쁺,�떆�옣,�궗濡�,swot,stp,4p / �븳以묒씪 �빆怨듭옄�쑀�솕 (Open sky) �빆怨듭궛�뾽媛쒕줎 Contents Korea Aerospace University Introduction (�빆怨� �옄�쑀�솕) �룞遺곸븘 �빆怨� �옄�쑀�솕�쓽 �븘�슂�꽦 �빆怨� �옄�쑀�솕濡쒖쓽 �젒洹쇰갑踰� �븳援��쓽 �빆怨듈�� |
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| ���4) �슚�냼�뿉 �쓽�빐 �떒諛깆쭏�쓣 �옒�씪 留뚮뱺 Peptide瑜� MALDI-TOF-MS 諛⑸쾿�뿉 �쓽�븳 Peptide Mass Map�쓣 �넻�빐 �룞�젙�븯怨�, 寃쎌슦�뿉 �뵲�씪�꽌�뒗 Nanoelectospray Tandem MS 諛⑸쾿�뿉 �쓽�븳 Sequencing�쓣 �넻�빐 �룞�젙�븳�떎. 3. �떇臾쇱뿉�꽌�쓽 �봽濡쒗뀒�샂 �뿰援� �쁽�솴怨� 媛��뒫�꽦 1) Arabidopsis�쓽 寃쎌슦�뒗 120 Mb�쓽 Genome�뿉 20,00媛쒖쓽 �쑀�쟾�옄 |
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| [�궗�쉶怨쇳븰] Molecular biology�뀫 Omics �쁽�옱 �뿰援� �룞�뼢 / List �뀪. Genomics -2- Genomics���-2- 援��궡, �쇅 Genomics �뿰援� �쁽�솴-2- Genomics �뿰援ъ쓽 �솢�슜諛⑹븞-3- �뀫. Proteomics -5- Proteomics���-5- 援��궡, �쇅 proteomics �뿰援� �쁽�솴-6- proteomics �뿰援ъ쓽 �솢�슜諛⑹븞-7- �뀬. Metabolomics -9- Metabolomics���-9- 援��궡, �쇅 Metabolomics �뿰援� �쁽�솴-9- Metabolomics �뿰援ъ쓽 �솢�슜諛⑹븞-9- �뀭. Reference -10- �뀪. Genomics Genomics��� g��� |
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