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1. ¹ßÈ¿À¯ÀÇ ¿µ¾çÀû °¡Ä¡
1.1. B vitamins
1.2. Lactose

1.3. Protein

1.4. Lipids

1.5. Minerals

2. Àå±â´É¿¡ °ü·ÃµÈ ¹ßÈ¿À¯ÀÇ ±â´É
2.1. Gut microflora
2.2. Gut-associated immune response
2.3. Laxation
3. ¹ßÈ¿À¯¿Í Àå Áúȯ
3.1. Lactase deficiency and lactose maldigestion
3.2. Diarrheal diseases
3.3. Colon cancer
3.4. Allergic reactions
3.5. Safety
¥². °á ·Ð
¥³. Reference
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Àΰ£ÀÇ Àå³» ¼¼±ÕÃÑ°ú ÀåÀ¸·Î µé¾î°¡´Â À½½Ä¹°ÀÇ ¿ä¼Òµé Áß¿¡´Â °Ç°­¿¡ À̷ӱ⵵ÇÏ°í ÇØ·Î¿ï ¼öµµ ÀÖ´Ù. Yogurt¿Í °°Àº À¯Á¦Ç°ÀÇ ¹ßÈ¿¿¡ ÀÌ¿ëµÇ´Â ƯÁ¤ ¹ÚÅ׸®¾Æ°¡ antipathogenic, antiinflammatoryÇÑ ¼º°ÝÀ» °¡Áø´Ù´Â Áõ°Å°¡ ¸¹´Ù. ÀÌµé ¹Ì»ý¹°µéÀº Àå³»¿¡ º´¿ø¼ºÀÌ ÀÖ´Â ¹ÚÅ׸®¾ÆµéÀÌ ¹ø½ÄÇÏ´Â °Í¿¡ ´ëÇÑ ÀúÇ×¼ºÀ» Áõ´ë½ÃÄÑÁֹǷΠÁúȯÀ» ¿¹¹æÇÏ´Â µ¥¿¡ ÀÌ¿ëµÉ ¼ö À־ probiotics¶ó ºÎ¸¥´Ù. Probiotics´Â ±âº»ÀûÀÎ ¿µ¾ç»óŸ¦ ³Ñ¾î °Ç°­¿¡ ÀÌÁ¡À» °¡Á®´ÙÁÙ ¼ö ÀÖ´Â »ì¾ÆÀÖ´Â ¹Ì»ý¹°µé·Î Á¤ÀǵȴÙ.

Yogurt´Â Probiotics¸¦ Æ÷ÇÔÇÏ´Â ½ÄÇ°À¸·Î Àß ¾Ë·ÁÁ® ÀÖ´Ù. Yogurt´Â Lactobacillus bulgaricus¿Í Streptococcus thermophilus¿¡ ÀÇÇØ ¿ìÀ¯ÀÇ Á¥»êÀÌ ¹ßÈ¿ µÇ¾îÁø °á°ú·Î ÀÀ°íµÈ À¯Á¦Ç°À¸·Î Á¤ÀǵȴÙ. Yogurt Á¦Ç°À» ¸¸µé ¶§ ¿ìÀ¯ ¹è¾ç¾× ¾È¿¡¼­ À¯»ê±Õµé »çÀÌ¿¡ °ø»ý°ü°è¸¦ ÀÌ·ç°Ô µÈ´Ù. ±×·¯¹Ç·Î ¼±ÅÃµÈ À¯»ê±Õ mixture´Â acid »ý¼º¹°À» ¸¸µå´Â È¿À²À» ³ôÀÌ°í ¼­·Î º¸¿ÏÀÛ¿ëÀ» Çϴµ¥ ÀÌ¿ëµÈ´Ù. °Ô´Ù°¡ À§ÀåÀÇ ³ôÀº »ê¼ºÁ¶°Ç¿¡¼­ »ì¾Æ³²´Â À¯»ê±ÕÀÇ ¼ö¸¦ Áõ°¡½ÃÅ°±â À§ÇØ Àΰ£ÀÇ Àå³»¿¡ Á¸ÀçÇÏ´Â ¾î¶² À¯»ê±ÕÁ¾µéÀÌ Yogurt Á¦Ç°À» ¸¸µå´Âµ¥ ÀÌ¿ëµÇ¾î ¡¦(»ý·«)
Âü°í¹®Çå

1. Perdigon G, Alvarez S, Rachid M, Aguero G, Gobbato NJ. Immune system stimulation by probiotics. J Dairy Sci 1995;78:1597–606.

2. Crittenden RG, Martinez NR, Playne MJ. Synthesis and utilisation of folate by yoghurt starter cultures and probiotic bacteria. Int J Food Microbiol 2003;80:217–22.

3. Gaudichon C, Mahé S, Roos N, et al. Exogenous and endogenous nitrogen flow rates and level of protein hydrolysis in the human jejunum after [15N] milk and [15N] yogurt ingestion. Br J Nutr 1995;74: 251–60.

4. Jiang J, Wolk A, Vessby B. Relation between the intake of milk fat and the occurrence of conjugated linoleic acid in human adipose tissue. Am J Clin Nutr 1999;70:21–7.

5. KempMQ,Jeffy BD, Romagnolo DF. Conjugated linoleic acid inhibits cell proliferation through a p53-dependent mechanism: effects on the expression of G1-restriction points in breast and colon cancer cells. J Nutr 2003;133:3670–7.

6. Ervin RB, Kennedy-Stephenson J. Mineral intakes of elderly adult supplement and non-supplement users in the third National Health and Nutrition Examination Survey. J Nutr 2002;132:3422–7.

7. Bronner F, Pansu D. Nutritional aspects of calcium absorption. J Nutr 1999;129:9–12.

8. Duez H, Pelletier H, Cools S, et al. A colony immunoblotting method for quantitative detection of a Bifidobacterium animalis probiotic strain in human faeces. J Appl Microbiol 2000;88:1019–27.

9. Plant L, Conway P. Association of Lactobacillus spp. with Peyer¡¯s patches in mice. Clin Diagn LAB Immunol 2001;8:320–4.

10. Kankaanpa¡§a¡§ P, Yang B, Kallio H, Isolauri E, Salminen S. Effects of polyunsaturated fatty acids in growth medium on lipid composition and on physicochemical surface properties of Lactobacilli. Appl Env Microbiol 2004;70:129–36.

11. Macpherson AJ, Gatto D, Sainsbury E, Harriman GR, Hengartner H, 254 ADOLFSSON ET AL Zinkernagel RM. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science 2000;288: 2222–6.

12. Solis-Pereyra B, Aattouri N, Lemonnier D. Role of food in the stimulation of cytokine production. Am J Clin Nutr 1997;66(suppl): 521S–5S.

13. Borruel N, Carol M, Casellas F, et al. Increased mucosal tumour necrosis factor alpha production in Crohn¡¯s disease can be downregulated ex vivo by probiotic bacteria. Gut 2002;51:659–64.

14. Beharka AA, Paiva S, Leka LS, Ribaya-Mercado JD, Russell RM, Nibkin Meydani S. Effect of age on the gastrointestinal-associated mucosal immune response of humans. J Gerontol A Biol Sci Med Sci 2001;56:B218–23.

15. AjueborMN,SwainMG.Role of chemokines and chemokine receptors in the gastrointestinal tract. Immunology 2002;105:137–43.

16. Marteau P, Cuillerier E, Meance S, et al. Bifidobacterium animalis strain DN-173 010 shortens the colonic transit time in healthy women: a double-blind, randomized, controlled study. Aliment Pharmacol Ther 2002;16:587–93.

17. Thoreux K, Balas D, Bouley C, Senegas-Balas F. Diet supplemented with yoghurt or milk fermented by Lactobacillus casei DN-114 001 stimulates growth and brush-border enzyme activities in mouse small intestine. Digestion 1998;59:349–59.

18. Van NeilCW,Feudtner C, GarrisonMM,Christakis DA. Lactobacillus therapy for acute infectious diarrhea in children: a meta-analysis. Pediatrics 2002;109:678–84.

19. Shornikova AV, Isolauri E, Burkanova L, Lukovnikova S, Vesikari T. A trial in the Karelian Republic of oral rehydration and Lactobacillus GG for treatment of acute diarrhoea. Acta Paediatr 1997;86:460–5.

20. D¡¯Souza AL, Rajkumar C, Cooke J, Bulpitt CJ. Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis. BMJ 2002;324:1–6.
21. Vanderhoof JA, Whitney DB, Antonson DL, Hanner TL, Lupo JV, Young RJ. Lactobacillus GG in the prevention of antibiotic-associated diarrhoea in children. J Pediatr 1999;135:356–68.
22. National Cancer Institute. SEER Cancer Incidence Public-Use Database, 1973-1996, August 1998 Submission. Bethesda, MD: US Department of Health and Human Services, Public Health Service, 1999.

23. Wollowski I, Ji S, Bakalinsky AT, Neudecker C, Pool-Zobel BL. Bacteria used for the production of yogurt inactivate carcinogens and prevent DNA damage in the colon of rats. J Nutr 1999;129:77–82.

24.Shackelford LA, Rao DR, Chawan CB, Pulusani SR. Effect of feeding fermented milk on the incidence of chemically induced colon tumors in rats. Nutr Cancer 1983;5:159–64.

25. Kim DH, Jin YH. Intestinal bacterial beta-glucuronidase activity of patients with colon cancer. Arch Pharm Res 2001;24:564–7.

26. Rafter JJ. The role of lactic acid bacteria in colon cancer prevention. Scand J Gastroenterol 1995;30:497–502.

27. Kallioma¡§ki M, Isolauri E. Role of intestinal flora in the development of allergy. Curr Opin Allergy Clin Immunol 2003;3:15–20.

28. Kirjavainen PV, Salminen SJ, Isolauri E. Probiotic bacteria in the management of atopic disease: underscoring the importance of viability. J Pediatr Gastroenterol Nutr 2003;36:223–7.

29. Isolauri E. Studies on Lactobacillus GG in food hypersensitivity disorders. Nutr Today 1996;31:28S–31S.
30. Miettinen M, Matikainen S, Vuopio-Varkila J, et al. Lactobacilli and streptococci induce interleukin-12 (IL-12), IL-18, and gamma interferon production in human peripheral blood mononuclear cells. Infect Immun 1998;66:6058–62.

31. Shida K, Makino K, Morishita A, et al. Lactobacillus casei inhibits antigen-induced IgE secretion through regulation of cytokine production in murine splenocyte cultures. Int Arch Allergy Immunol 1998; 115:278–87.

32. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002; 78:366–7.
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36. Presterl E, Kneifel W, Mayer HK, Zehetgruber M, Makristathis A, Graninger W. Endocarditis by Lactobacillus rhamnosus due to yogurt ingestion? Scand J Infect Dis 2001;33:710–4.



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