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Synthesis of substituted Dihydro-1,3-benzoxazine(¿¹ºñº¸°í¼­)

Synthesis of substituted Dihydro-1,3-benzoxazine(¿¹ºñº¸°í¼­)

Synthesis of substituted Dihydro-1,3-benzoxazine(¿¹ºñº¸°í¼­) / 1. ½ÇÇèÁ¦¸ñ 2. ½ÇÇè¸ñÇ¥ 3. ÀÌ·Ð 4. ½Ã¾à ¹× ±â±¸ 5. ½ÇÇè¹æ¹ý 6. Âü°í¹®Çå / 1. ½ÇÇèÁ¦¸ñ ½ÇÇèÁ¦¸ñÀº `Dihydro-1,3-benzoxazineÀÇ Ä¡È¯À¯µµÇÕ¼º`ÀÌ´Ù. ÀÌ ¿¬±¸ÀÇ ÁÖµÈ ¸ñÀûÀº ´Ù¾çÇÑ Ä¡È¯±âµéÀÌ µµÀÔµÈ Dihydro-1,3-benzoxazine ±¸Á¶ÀÇ À¯µµÇÕ¼ºÀ» ÅëÇØ ÀÌ È­ÇÕ¹°ÀÇ ¹°¸®È­ÇÐÀû ¼ºÁú°ú »ý¹°ÇÐÀû È°¼ºÀ» Æò°¡ÇÏ¡¦
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Synthesis of the substituted Dihydro-1,3-benzoxazine(°á°úº¸°í¼­)

Synthesis of the substituted Dihydro-1,3-benzoxazine(°á°úº¸°í¼­)

Synthesis of the substituted Dihydro-1,3-benzoxazine(°á°úº¸°í¼­) / 1. ½ÇÇè°á°ú 2. Áú¹® 3. ÅäÀÇ 4. Âü°í¹®Çå / 1. ½ÇÇè°á°ú À̹ø ½ÇÇè¿¡¼­´Â ´ëüµÈ µðÇÏÀ̵å·Î-1,3-º¥Á¶¿Á»çÁøÀÇ ÇÕ¼ºÀ» ¼öÇàÇÏ¿´´Ù. ¹ÝÀÀÀº ÀϹÝÀûÀ¸·Î µÎ °¡Áö ÁÖ¿ä Àü±¸Ã¼ÀÇ ¹ÝÀÀÀ» ÅëÇØ ÁøÇàµÇ¾úÀ¸¸ç, °¢ Àü±¸Ã¼´Â À¯µµÃ¼ °£ÀÇ »óÈ£ÀÛ¿ëÀ» ÅëÇØ ÃÖÁ¾ »ý¼º¹°ÀÎ µðÇÏÀ̵å·Î-1,3-º¥Á¶¿Á»çÁøÀ» Çü¼ºÇÏ¿´´Ù. ¹Ý¡¦
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Synthesis of the Substituted Dihydro-1,3-benzoxazine ¿¹ºñº¸°í¼­

Synthesis of the Substituted Dihydro-1,3-benzoxazine ¿¹ºñº¸°í¼­

Synthesis of the Substituted Dihydro-1,3-benzoxazine ¿¹ºñº¸°í¼­ / 1. ½ÇÇèÁ¦¸ñ 2. ½ÇÇè¸ñÇ¥ 3. ½ÇÇèÀÌ·Ð 1) AmineÀÇ Ä£ÇÙ¼º ÷°¡ ¹ÝÀÀ 2) Imine Çü¼º mechanism 3) Enamine Çü¼º mechanism 4) ½ÇÇè mechanism 4. ½Ã¾à ¹× ±â±¸ 1) ½Ã¾à 2) ±â±¸ 5. ½ÇÇè¹æ¹ý 6. Âü°í¹®Çå / 1. ½ÇÇèÁ¦¸ñ ½ÇÇè Á¦¸ñÀº ¡°Substituted Dihydro-1,3-benzoxazineÀÇ ÇÕ¼º¡±ÀÌ´Ù. ÀÌ ¿¬±¸ÀÇ¡¦
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Synthesis of the Substituted Dihydro-1,3-benzoxazine °á°úº¸°í¼­

Synthesis of the Substituted Dihydro-1,3-benzoxazine °á°úº¸°í¼­

Synthesis of the Substituted Dihydro-1,3-benzoxazine °á°úº¸°í¼­ / 1. ½ÇÇè°á°ú 2. Áú¹® 3. ÅäÀÇ / 1. ½ÇÇè°á°ú ½ÇÇè °á°ú¿¡¼­´Â ´Ù¾çÇÑ ½Ã¾à°ú ¹ÝÀÀ Á¶°ÇÀ» ÅëÇØ ¾ò¾îÁø substituted dihydro-1,3-benzoxazineÀÇ ÇÕ¼º °úÁ¤°ú ±× °á°ú¸¦ »ó¼¼È÷ »ìÆ캻´Ù. ÇÕ¼ºÀÇ Ã¹ ´Ü°è·Î ½ÃÀÛÇÑ Àü±¸Ã¼ÀÇ Á¶ÇÕÀº ¹ÝÀÀÀÌ Àß ÁøÇàµÇµµ·Ï ÃÖÀûÈ­ÇÏ¿´°í, ¹ÝÀÀ ¿Âµµ¿Í ½Ã°£, ±×¸®°í Ã˸ÅÀÇ ¿µÇâ µîÀ»¡¦
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Synthesis of the Substituted Dihydro-1,3-benzoxazine °á°úº¸°í¼­ (1)

Synthesis of the Substituted Dihydro-1,3-benzoxazine °á°úº¸°í¼­ (1)

Synthesis of the Substituted Dihydro-1,3-benzoxazine °á°úº¸°í¼­ (1) / 1. ½ÇÇè°á°ú 2. Áú¹® 3. ÅäÀÇ 4. Âü°í¹®Çå / 1. ½ÇÇè°á°ú ½ÇÇè°á°ú ½ÇÇè¿¡¼­ ÇÕ¼ºÇÑ Ä¡È¯µÈ µðÇÏÀ̵å·Î-1,3-º¥Á¶¿Á»çÁøÀÇ °á°ú´Â Ÿ´ç¼º°ú ½Å·Ú¼ºÀ» È®º¸ÇÏ´Â µ¥ Áß¿äÇÑ ±âÃÊ ÀÚ·á°¡ µÇ¾ú´Ù. ¸ÕÀú, ÇÕ¼º °úÁ¤À» ÅëÇØ È®º¸ÇÑ ½Ã·áÀÇ ¿Ü°üÀº ¿¬ÇÑ È²»ö¿¡¼­ ÁøÇÑ ³ë¶õ»öÀÇ °áÁ¤¼º °íü ÇüÅ·Π³ªÅ¸³µ´Ù. ÀÌ ¡¦
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Synthesis of the Substituted Dihydro-1,3-benzoxazine °á°úº¸°í¼­

Synthesis of the Substituted Dihydro-1,3-benzoxazine °á°úº¸°í¼­

Synthesis of the Substituted Dihydro-1,3-benzoxazine °á°úº¸°í¼­ / 1. ½ÇÇè°á°ú 1) ¼öµæ·ü 2) m.p. 2. Áú¹® 1) »ý¼º¹°¿¡ ´ëÇØ ¿¹»óµÇ´Â 1H NMR ½ºÆåÆ®·³À» ±×·Áº¸½Ã¿À. 2) imine°ú enamineÀÌ aldehyde¿¡¼­ ÇÕ¼ºµÇ´Â mechanismÀ» Á¦½ÃÇϽÿÀ. 3. ÅäÀÇ 4. Âü°í¹®Çå / 1. ½ÇÇè°á°ú À̹ø ½ÇÇè¿¡¼­´Â substituted dihydro-1,3-benzoxazineÀÇ ÇÕ¼ºÀ» ¸ñÇ¥·Î ÇÏ¿´´Ù. ½ÇÇèÀº ´Ù¡¦
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synthesis of the substituted dihydro-1,3-benzoxazine ¿¹ºñº¸°í¼­

synthesis of the substituted dihydro-1,3-benzoxazine ¿¹ºñº¸°í¼­

synthesis of the substituted dihydro-1,3-benzoxazine ¿¹ºñº¸°í¼­ / 1. ½ÇÇè¸ñÇ¥ 2. ½ÇÇèÀÌ·Ð 3. ½Ã¾à ¹× ±â±¸ 4. ½ÇÇè¹æ¹ý 5. Âü°í¹®Çå / 1. ½ÇÇè¸ñÇ¥ º» ½ÇÇèÀÇ ¸ñÇ¥´Â substituted dihydro-1,3-benzoxazineÀÇ ÇÕ¼ºÀ» ÅëÇØ ÀÌ È­ÇÕ¹°ÀÇ Æ¯¼º°ú ¹ÝÀÀ¼ºÀ» ÀÌÇØÇÏ°í, À̸¦ ±â¹ÝÀ¸·Î ÇÑ È­ÇÕ¹°ÀÇ ´Ù¾çÇÑ ÀÀ¿ë °¡´É¼ºÀ» Ž»öÇÏ´Â °ÍÀÌ´Ù. Dihydro-1,3-benzoxazine À¯µµÃ¼´Â ¾à¸®ÇС¦
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Synthesis of the Substituted Dihydro-1,3-benzoxazine ¿¹ºñº¸°í¼­ (1)

Synthesis of the Substituted Dihydro-1,3-benzoxazine ¿¹ºñº¸°í¼­ (1)

Synthesis of the Substituted Dihydro-1,3-benzoxazine ¿¹ºñº¸°í¼­ (1) / 1. ½ÇÇèÁ¦¸ñ 2. ½ÇÇè¸ñÀû 3. ÀÌ·Ð 4. ½Ã¾à ¹× ±â±¸ 5. ½ÇÇè¹æ¹ý / 1. ½ÇÇèÁ¦¸ñ ½ÇÇèÁ¦¸ñÀº `Substituted Dihydro-1,3-benzoxazineÀÇ ÇÕ¼º`ÀÌ´Ù. º» ½ÇÇèÀº ġȯ±â µµÀÔÀÌ °¡´ÉÇÑ µðÇÏÀ̵å·Î-1,3-º¥Á¶¿Á»çÁø À¯µµÃ¼ÀÇ ÇÕ¼ºÀ» ¸ñÇ¥·Î Çϸç, ÀÌ È­ÇÕ¹°Àº ÀǾà È­ÇÐ ¹× Àç·á °úÇÐ ºÐ¾ß¿¡¼­ Áß¿äÇÑ ¿ªÇÒÀ» ÇÒ ¡¦
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synthesis of the substituted dihydro-1,3-benzoxazine

synthesis of the substituted dihydro-1,3-benzoxazine

synthesis of the substituted dihydro-1,3-benzoxazine / 1. ½ÇÇèÀÌ·Ð 2. ½Ã¾à ¹× ÃÊÀÚ 3. ½ÇÇè¹æ¹ý / 1. ½ÇÇèÀÌ·Ð ½ÇÇèÀÌ·Ð ´ëüµÈ µðÇÏÀ̵å·Î-1,3-º¥Á¶»çÁøÀÇ ÇÕ¼º¿¡´Â ¿©·¯ È­ÇÐÀû ¹æ¹ýÀÌ Á¸ÀçÇϴµ¥, ÀÌ È­ÇÕ¹°Àº ¾à¹° ¹ß°ß, °íºÐÀÚ ¹× ¼ÒÀç °úÇп¡¼­ Áß¿äÇÑ ¿ªÇÒÀ» ÇÑ´Ù. µðÇÏÀ̵å·Î-1,3-º¥Á¶»çÁøÀº º¥Á¶»çÁøÀÇ À¯µµÃ¼·Î, ±× ±¸Á¶´Â 1,3-º¥Á¨ °í¸®¿¡ µÎ °³ÀÇ »ê¼Ò ¿øÀÚ°¡ °á¡¦
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Sythesis of the substituted dihydro-1,3-benzoxazine À¯±â½ÇÇ躸°í¼­

Sythesis of the substituted dihydro-1,3-benzoxazine À¯±â½ÇÇ躸°í¼­

Sythesis of the substituted dihydro-1,3-benzoxazine À¯±â½ÇÇ躸°í¼­ / 1. ÀÌ·Ð 2. ½Ã¾à ¹× ½ÇÇè¹æ¹ý 3. ½ÇÇè °á°ú ¹× °íÂû 4. Âü°í¹®Çå / 1. ÀÌ·Ð ÀÌ·Ð ´ëüµÈ ´ÙÀÌÇÏÀ̵å·Î-1,3-º¥Á¶¿Á»çÁøÀÇ ÇÕ¼ºÀº À¯±â È­ÇÕ¹°ÀÇ ±¸Á¶Àû ´Ù¾ç¼ºÀ» Áõ°¡½ÃÅ°°í, ÀÌ·¯ÇÑ È­ÇÕ¹°ÀÌ °¡Áö´Â »ý¸®È°¼º°ú ¹°¸®È­ÇÐÀû Ư¼ºÀ» ¿¬±¸ÇÏ´Â µ¥ Áß¿äÇÑ ¿ªÇÒÀ» ÇÑ´Ù. ´ÙÀÌÇÏÀ̵å·Î-1,3-º¥Á¶¿Á»çÁøÀº ƯÈ÷ »ý¡¦
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